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| 소속 :
LG생명과학 |
주관심분야 :
Drug delivery , Tissue engineering , Molecular imaging , Drug eluting balloon , Pharmaceutical preformulation , Oral dosage form |
이메일 :
timeium.LG@gmail.com |
| 학력 :
비공개 |
경력 :
비공개 |
논문 :
. K. Na, K-H. Park, S. Kim, Y.H. Bae. Self-assembled hydrogel nanoparticles from curdlan derivatives; characterization, anti-cancer drug release and interaction with a hepatoma cell line (HepG2). J. Control. Release 2000, 69, 225–236.
2. K-H. Park, S. Kim, Y.H. Bae. Effect of sulfonylurea-conjugated polymer on insulin secretion from insulinoma cell line MIN6 cells. J. Biomed. Mater. Res. 2001, 55, 72–78.
3. S. Kim, S.Y. Chae, K. Na, S.W. Kim, Y.H. Bae. Insulinotropic activity of sulfonylurea/pullulan conjugate in rat islet microcapsule. Biomaterials 2003, 24, 4843–4851.
4. S. Kim, Y.H. Bae. Visual evidence and quantification of interaction of polymeric sulfonylurea with pancreatic islet. Biomacromolecules 2003, 4, 1550–1557.
5. S. Kim, Y.H. Bae. Long-term insulinotropic activity of glucagon-like peptide-1/polymer conjugate on islet microcapsules. Tissue Eng. 2004, 10, 1607–1616.
6. S. Kim, S.W. Kim, Y.H. Bae. Synthesis, bioactivity, and specificity of a glucagon-like peptide-1 (7-37)/polymer conjugate to isolated rat islets. Biomaterials 2005, 26, 3597-3606.
7. K-H. Park, W.J. Sung, S. Kim, D.H. Kim, T. Akaike, H-M. Chung. Specific interaction of mannosylated glycopolymers with macrophage cells mediated by mannose receptors. J. Biosci. Bioeng. 2005, 99, 285–289.
8. H.C. Kang, S. Kim, M. Lee, Y.H. Bae. Polymeric gene carrier for insulin secreting cells; Poly(L-lysine)-g-sulfonylurea for receptor mediated transfection. J. Control. Release 2005, 105, 164–176.
9. K-H. Park, K. Na, S.Y. Jung, S. Kim, K.H. Park, K.Y. Cha, H-M. Chung. Insulinoma cell line (MIN6) adhesion and spreading mediated by Arg-Gly-Asp (RGD) sequence conjugated in thermo-reversible gel. J. Biosci. Bioeng. 2005, 99, 598–602.
10. K. Kim, J-H. Kim, S. Kim, H. Chung, K. Choi, I.C. Kwon, J.H. Park, Y-S. Kim, R-W. Park, I-S. Kim, S.Y. Jeong. Self-assembled nanoparticles of bile-acid modified glycol chitosans and their applications for cancer therapy. Macromol. Res. 2005, 13, 167–175 (Review paper).
11. K-H. Park, K. Na, S. Kim, S.Y. Jung, K.H. Park, H-M. Chung. Phenotype of hepatocyte shperiods behaviors within thermo-sensitive poly(NiPAAm-co-AAc-g-GRGDS) hydrogel as a cell delivery vehicle. Biotech. Lett. 2005, 27, 1081-1086.
12. Y.Y. Kim, S.Y. Chae, S. Kim, Y. Byun, Y.H. Bae. Improved phenotype of rat islets in a macrocapsules by co-encapsulation with cross-linked Hb. J. Biomater. Sci. Polymer Ed. 2005, 16, 1521-1535.
13. K. Kim, M. Lee, H. Park, J-H. Kim, S. Kim, H. Chung, K.W. Choi, I-S. Kim, B.I. Seong, I.C. Kwon. Smart polymeric nanoparticles for apoptosis imaging. J. Am. Chem. Soc. 2006, 128, 3490-3491.
14. J-H. Kim, Y-S. Kim, S. Kim, K. Kim, J.H. Park, K.W. Choi, H. Chung, S.Y. Jeong, R-W. Park, I-S. Kim, I.C. Kwon. Hydrophobically modified glycol chitosan nanoparticles as carriers for paclitaxel. J. Control. Release 2006, 111, 228-234.
15. K. Na, J.H. Park, S. Kim, B.K. Sun, D.G. Woo, H-M. Chung, K-H. Park. Delivery of dexamethasone, ascorbate, and growth factor (TGF β-3) in thermo-reversible hydrogel constructs embedded with rabbit chondrocytes. Biomaterials 2006, 27, 5951-5957.
16. H-C. Song, K. Na, K-H. Park, C-H. Shin, H-S. Bom, D. Kang, S. Kim, E.S. Lee, D.H. Lee. Intratumoral administration of Rhenium-188-labeled pullulan acetate nanoparticles (PAN) in mice bearing CT-26 cancer cells for suppression of tumor growth. J. Microbiol. Biotechnol. 2006, 16, 1491-1498.
17. K. Na, S. Kim, D.G. Woo, B.K. Sun, H.N. Yang, H-M. Chung, K-H. Park. Synergistic effect of TGFβ-3 on chondrogenic differentiation of rabbit chondrocytes in thermo-reversible hydrogel constructs blended with hyaluronic acid by in vivo test. J. Biotechnol. 2007, 128, 412-422.
18. S. Kim, Y.S. Nam, Y.J. Min, J-H. Kim, K. Kim, K.W. Choi, I. Noh, I.C. Kwon. Release profile of a model protein drug depending on the stability of microspheres based on polyelectrolyte complex. Key Eng. Mater. 2007, 342-343, 505-508.
19. K. Na, S. Kim, B.K. Sun, D.G. Woo, H.N. Yang, H-M. Chung, K-H. Park. Osteogenic differentiation of rabbit mesenchymal stem cells in thermo-reversible hydrogel constructs containing hydroxyapatite and bone morphogenic protein-2 (BMP-2). Biomaterials 2007, 28, 2631-2637.
20. E.S. Lee, K-H. Park, D. Kang, I.S. Park, H.Y. Min, D.H. Lee, S. Kim, J-H. Kim, K. Na. Protein complexed with chondroitin sulfate in poly(lactide-co-glycolide) microspheres. Biomaterials 2007, 28, 2754-2762.
21. K. Na, S. Kim, K. Park, K. Kim, D.G. Woo, I.C. Kwon, H.-M. Chung, K.-H. Park. Heparin/poly(l-lysine) nanoparticle-coated polymeric microspheres for stem-cell therapy. J. Am. Chem. Soc. 2007, 129, 5788-5789.
22. K.-H. Park, H.-C. Song, K. Na, H.-S. Bom, K.H. Lee, S. Kim, D. Kang, D.H. Lee. Ionic strength-sensitive pullulan acetate nanoparticles (PAN) for intratumoral administration of radioisotope: Ionic strength-dependent aggregation behavior and 99mTechnitium retention property. Colloids Surf. B Biointerface. 2007, 59, 16-23.
23. K. Na, S. Kim, D.G. Woo, B.K. Sun, H.N. Yang, H.-M. Chung, K.-H. Park. Combination material delivery of dexamethasone and growth factor in hydrogel blended with hyaluronic acid constructs for neocartilage formation. J. Biomed. Mater. Res. A 2007, 83, 779-786.
24. S.-J. Choi, K. Na, S. Kim, D.G. Woo, B.K. Sun, H.-M. Chung, K.-H. Park. Combination of ascorbate and growth factor (TGF β-3) in thermo-reversible hydrogel constructs embedded with rabbit chondrocytes for neocartilage formation. J. Biomed. Mater. Res. A 2007, 83, 897-905.
25. K. Na, S.-J. Choi, S. Kim, B.K. Sun, D.G. Woo, H.-M. Chung, K.-H. Park. Enhancement of cell proliferation and differentiation by combination of ascorbate and dexamethasone in thermo-reversible hydrogel constructs embedded with rabbit chondrocytes. Biotechnol. Lett. 2007, 29, 1453-1457.
26. K. Na, S. Kim, B.K. Sun, D.G. Woo, H.-M. Chung, K.-H. Park. Blended constructs consisting of thermo-reversible hydrogel and heparinized nanoparticles for increasing the proliferation activity of the rabbit chondrocyte in vivo test. Biotechnol. Lett. 2007, 29, 1447-1452.
27. K.M. Huh, H.S. Min, S.C. Lee, H.J. Lee, S. Kim, K. Park. A new hydrophilic block copolymer micelle system for aqueous solubilization of paclitaxel. J. Control. Release 2008, 126, 122-129.
28. S. Kim, K.M. Park, J.Y. Ko, I.C. Kwon, H.G. Cho, D. Kang, I.T. Yu, K. Kim, K. Na. Minimalism in fabrication of self-organized nanogels holding anti-cancer drug and targeting moiety. Colloids Surf. B Biointerf. 2008, 63, 55-63.
29. H. Chen, S. Kim, W. He, S. Wang, P.S. Low, K. Park, J.X. Cheng. Fast release of lipophilic agents from circulating PEG-PDLLA micelles revealed by in vivo Förster resonance energy transfer imaging. Langmuir 2008, 24, 5213-5217 (Issue Cover).
30. H. Chen, S. Kim, L. Li, S. Wang, K. Park, J.X. Cheng. Release of hydrophobic molecules from polymer micelles into cell membranes revealed by Förster resonance energy transfer imaging. Proc. Natl. Acad. Sci. USA 2008, 105, 6596-6601.
31. K. Na, S. Kim, B.K. Sun, D.G. Woo, H.N. Yang, H.-M. Chung, K.-H. Park. Bioimaging of dexamethasone and TGF β-1 and its biological activities of chondrogenic differentiation in hydrogel constructs. J. Biomed. Mater. Res. A 2008, 87, 283-289.
32. S. Kim, J.Y. Kim, K.M. Huh, G. Acharya, K. Park. Hydrotropic polymer micelles containing acrylic acid moieties for oral delivery of paclitaxel. J. Control. Release 2008, 132, 222-229.
33. S. Kim, J.-H. Kim, O. Jeon, I.C. Kwon, K. Park. Engineered polymers for advanced drug delivery. Eur. J. Pharm. Biopharm. 2009, 71, 420-430.
34. S. Kim, Y. Shi, J.Y. Kim, K. Park, J-X, Cheng. Overcoming the barriers in micellar drug delivery: Loading efficiency, in vivo stability, and micelle-cell interaction. Expert Opin. Drug Deliv. 2010, 7, 49-62.
35. Y. Shi, S. Kim, T.B. Huff, R.B. Borgens, K. Park, R. Shi, J.X. Cheng. Effective repair of traumatically injured spinal cord by block copolymer micelles: A pilot study. Nat. Nanotech. 2010, 5, 80-87.
36. M. Ye, S. Kim, K. Park. Issues in long-term protein delivery using biodegradable microparticles. J. Control. Release 2010, 146, 241-260.
37. J.Y. Kim, S. Kim, R. Pinal, M. Papp, K. Park. Hydrotropic solubilization for various poorly water-soluble drugs. J. Pharm. Sci. 2010, 99, 3953-3965.
38. Y.S. Nam, S. Kim, I. Noh, M.S. Bae, I.K. Kwon. Mechanism of albumin release from alginate and chitosan beads fabricated in dual layers. Macromol. Res. 2011, 19, 476-482.
39. Y. Lu, S. Kim, K. Park. In vitro-in vivo correlation: Perspectives on model development. Int. J. Pharm. 2011, 418, 142-148.
40. Y.H. Yun, B.K. Lee, J.S. Choi, S. Kim, B. Yoo, Y.S. Kim, K. Park, Y.W. Cho. A glucose sensor fabricated by piezoelectric inkjet printing of conducting polymers and bienzymes. Anal. Sci. 2011, 27, 375-379.
41. J.Y. Kim, S. Kim, R. Pinal, K. Park. Hydrotropic polymer micelles as universal vehicles for delivery of poorly-soluble drugs. J. Control. Release 2011, 152, 13-20.
42. K. Vedantham, S. Chaterji, S. Kim, K. Park. Development of a probucol-releasing antithrombogenic drug eluting stent. J. Biomed. Mater. Res. B Appl. Biomater. 2012, 100, 1068-1077.
43. S.Y. Lee, S. Kim, J.Y. Tyler, K. Park, J.X. Cheng. Blood-stable, tumor-adaptable disulfide bonded mPEG-(Cys)(4)-PDLLA micelles for chemotherapy. Biomaterials. 2013, 34, 552-561.
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